RPM of is available in remi repository and waiting for review for fedora >= 16 repository.
This mysqlnd extension handle load balancing betwwen master and slave servers, handled by the application, or transparently.
Pecl site: mysqlnd_ms
Documentation : Mysqlnd replication and load balancing plugin
Fedora review : Review request #742729
Installation, after the switch from php-mysql to php-mysqlnd :
yum --enablerepo=remi install...